Famous Funny Commercials

This is the ten of the most funny commercials that made me laugh and that are also famous, that have written history so to say. I hope you enjoy them as I did.

Funny Pranks

These are some of the best pranks of all time.

Sildenafil

What is Sildenafil?

Sildenafil is the active ingredient some of the medicine to treat erectile dysfunction and pulmonary arterial hypertension such as Viagra, Rivatio, Sildenafil and other. This active ingredient helps relax blood vessels and improves blood flow to the penis to allow for a harder and longer-lasting erection.
Nowadays many products are using this ingredient for benefit of making penis harder and longer-lasting erection in a different way that causes many health problems among the user of those products, sometimes it leads to dead by cardiac arrest while having intercourse and other.
So we have to know about this ingredient clearly before buying or using it and strictly follow your doctor’s advice.


Side effect of Sildenafil

The safety profile of sildenafil is based on 9570 patients from 74 double-blind, placebo-controlled clinical trials. The most commonly reported adverse events in clinical trials in patients treated with sildenafil were a headache, flushing, dyspepsia, nasal congestion, dizziness, nausea, hot flash, visual disturbance, cyanopsia, and blurred vision.
Organ system class affected and frequency reported during the study :
1. Very common (≥ 1/10)
- Nervous system: a headache
2. Common (≥ 1/100 and 1/1000)
- Nervous system : dizziness
- Eyes: alteration of color vision, visual disturbance, blurred vision
- Blood vessels: congestive flushes, hot flashes
- Gastro-intestinal: nausea, dyspepsia
- Respiratory: nasal congestion
3. Uncommon (≥1 / 1000 and 10 000)
- Infection and infestation : rhinitis
- Immune system: hypersensitivity
- Nervous system: somnolence, hypoesthesia
- Eyes: psoriasis, eye pain, photophobia, photopsia, ocular hyperemia, visual brilliance, conjunctivitis
- Ear and labyrinth: dizziness, tinnitus
- Heart: tachycardia, palpitation
- Blood vessel: hypertension, hypotension
- Respiratory: epistaxis, sinusale congestion
- Gastro-intestinal: gastroesophageal reflux disease, vomiting, upper abdominal pain, dry mouth
- Skin and subcutaneous tissue: rash
- Musculoskeletal and systemic: myalgia, extremities pains
- Urinary system: hematuria
- General: chest pain, fatigue, the sensation of heat
- Investigations: acceleration of heartbeat
4. Rare (≥ 1/10 000 and 1/100 000)
- Nervous system : stroke, transient ischemic attack, seizure, seizure recurrence, syncope
- Eyes: nonarteritic anterior ischemic optic neuropathy (NAION), retinal vascular occlusion, retinal hemorrhage, retinopathy of arteriosclerotic origin, retinal disorder, glaucoma, alteration of the visual field, diplopia, decrease of visual acuity, myopia, asthenopia, floating bodies glaucoma, iris abnormality, mydriasis, halos vision, eye edema, eye swelling, eye disorders, conjunctival hyperemia, eye irritation, abnormal eye sensation, eyelid edema, scleral discolouration - Ear and labyrinth: deafness
- Heart: sudden cardiac death, myocardial infarction, ventricular arrhythmia, atrial fibrillation, unstable angina
- Respiratory: pharyngeal constriction sensation, nasal edema, nasal dryness
- Gastro-intestinal: oral hypoaesthesia
- Skin and subcutaneous tissue: Stevens-Johnson syndrome (SJS), Lyell syndrome
- Reproduction organ and breast: penile hemorrhage, priapism, hematospermia, increased erection
- General: irritability


Mechanism of action of Sildenafil

Sildenafil is an oral treatment for erectile dysfunction. In natural conditions, that is, with sexual stimulation, it restores poor erectile function by increasing blood flow to the penis.
The physiological mechanism responsible for the erection of the penis involves the release of nitric oxide (NO) into the cavernous body during sexual stimulation. Nitric oxide activates the enzyme guanylate cyclase, resulting in increased concentrations of cyclic guanosine monophosphate (cGMP) inducing relaxation of the smooth muscles of the cavernous body and promoting blood flow.
Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5) in cavernous bodies; this is where PDE5 is responsible for the degradation of cGMP. Sildenafil has a peripheral action site on erections. Sildenafil has no direct relaxant effect on human cavernous body tissue alone, but it significantly accentuates the relaxing effects of NO on this tissue. When the NO / cGMP pathway is activated, such as during sexual stimulation, the inhibition of PDE5 by sildenafil results in an increase in cGMP concentrations in cavernous bodies. However, to produce its beneficial pharmacological effects, the sexual stimilation is needed.

Food that you can eat as much as you want without risk of gaining weight

How to eat and lose weight? How to stay slim without diets or the gym? There are foods you can eat without the risk of gaining weight.

Celery has anti-allergic and antiseptic properties. This plant can improve your digestion and overall health.

There are only 10 calories in 2 cups of arugula. It helps you get slimmer without damaging your health.

Scientists found that eggs keep you feeling full for longer periods than foods that contain more carbs. Mix the whites with a few tomatoes and get the healthiest omelet ever!

The salad is packed with vitamins A and C as well as folic acid and iron. It’s practically devoid of calories (10 to 20 calories, depending on the type).

Fresh, crunchy cucumbers have significant health benefits. The skin of a cucumber contains most of its nutritional value, particularly beta-carotene, which is good for your eyes.

Cauliflower is an excellent source of vitamins C and K. Also, it contains only 25 calories.

One tomato has about 25 calories. Tomatoes are full of lycopene, vitamins A, C, and B2, folic acid, fiber, chromium, and potassium.

Broccoli contains 31 calories, and it is one of the favorite foods of those who want to lose weight.

Oranges are one of the most delicious fruits. They are best known for their vitamin C content. By the way, the white stuff under the orange skin, the pith, is really good for you.

Kale, like any other edible seaweed, contains a large amount of iodine and it’s almost devoid of calories. It has about 32 calories.

Sugar snap peas are very low in calories: a cup of peas contains around 35 calories.

Grapefruits help to stabilize blood sugar levels. They’re full of vitamin C, and, due to their low caloric value, they can help you reduce those extra inches around your waist.

Melon contains over half the recommended daily value of vitamins A and C and only 55 calories. Melon is also very useful for preventing flu and improving the immune system.

Strawberries are rich in potassium and fiber and have an anti-inflammatory effect. It sounds surprising, but a couple of strawberries contain as much vitamin C as an orange.

Blackberries are full of antioxidants and vitamin C. Also, they have an amazing taste.

One cup of air-popped popcorn will never affect your body. This “movie snack” mostly consists of air, and you can enjoy eating it without fear of gaining extra weight.

Blueberries have more antioxidants than any other fruit. Therefore, a cup of blueberries will help you balance your diet.

Low Back Pain

Introduction
• Low back pain (LBP) is extremely common and includes a wide range of symptoms involving the lumbosacral spine and pelvic girdle
• Characterized by duration or associated symptoms
• Duration
– Acute ( least than 6 weeks)
– Subacute ( 6 weeks to 3 months)
– Chronic (more than 3 months)
• Associated symptoms
– Localized/nonspecific “mechanical” LBP
– Back pain with lower extremity symptoms
– Systemic and visceral symptoms
• There isn't the specific cause for most patients with LBP. Most cases resolve in 4 to 6 weeks
• Rule out “red” flag symptoms are needed for immediate intervention
• System(s) affected: musculoskeletal, neurologic
• Synonym(s): lumbago, lumbar sprain/strain, low back syndrome.

Etiology and Pathophysiology
A clear etiology is not found in most patients. Age-related degenerative changes of the lumbosacral spine and atrophy of supporting musculature may contribute.

Risk Factors
• Age
• Activity (lifting, sudden twisting, bending)
• Obesity
• Sedentary lifestyle
• Physically strenuous work
• Psychosocial factors—anxiety, depression, stress
• Smoking

General Prevention
• Maintain normal weight
• Adequate physical fitness and activity
• Stress reduction
• Proper lifting technique and good posture
• Smoking cessation
• There isn't sufficient evidence to recommend for, or against routine preventive measures in adults.

Some Types of Belly That Aren't Caused by Overweight

In Summer all of us want to look perfect however sometimes our bellies don’t seem to reduce in size despite our best effort. We sought the advice of James Duigan a star coach who trained Elle MacPherson and Rosie Huntington-Whiteley. And learned the most common causes of growth around the weight.

Love Handles

How does it look you have folds on your sides, and it’s usually caused by sedentary lifestyle, sweet tooth, excess alcohol consumption, lots of sugar and refined carbs cookies [cakes] and white bread or starchy carbs pasta and rice.
How to get rid of it
- drink less alcohol
Several glasses of wine drunk three to four times a week lead to a wine waist with a potbelly and fat size. Stop drinking altogether for two weeks, and then remember moderation.
- rethink your diet
Avoid special dietary products and the low-fat foods, add eggs, lean meat, and vegetables and healthy fats such as avocado, nuts and [high-fat] fish in your diet.
- find time for exercise
You don’t have to go to the gym long walks will do as well also you can perform lunges squats and reverse push-ups at home. Keep in mind that physical exercise and proper diet are enough. Both of these will reduce your belly in size and give you strength to go on.

Stress Belly

The fat is concentrated around the belly button and the belly is thick, not loose here are the factors that cause it
- chronic stress
- skipping meals
- drinking lots of coffee
- irritable bowel syndrome
- unhealthy food such as salted nuts and potato chips
No worries! There are some effective ways to get rid of it.
- go to bed early
You sleep little and poorly under stress which disrupts leptin production, a hormone that helps to regulate your appetite and metabolism. You need to sleep at least seven to eight hours every day and go to bed before midnight.
- relax before sleep
Breathing exercises, taking a bath, or meditation, all do the trick these useful habits will help you sleep well also. Limit your nightly coffee consumption; don’t drink more than two cups of coffee a day.
- don’t overexert your body with exercise
Excess Cardio only increases your cortisol levels, instead do yoga or take long walks even a gym session will calm you down but don’t overdo it.
- include magnesium in your diet
Magnesium is a relaxing mineral. You can find it in dark Green vegetables, nuts, and wheat bran. Also, do some yoga or stretching and drink chamomile tea before going to bed that will reduce cortisol and helps your body calm down.

Low Belly

How does it look? you’re slim but your lower belly protrudes a bit. You should know that it might be caused by recent motherhood, anonymous and overly exert of exercise, unchanging diet, spinal curvature.
We know some brilliant ways to get rid of it?
- a healthy diet and lots of fiber
Green leaves vegetables, whole-grain bread, and other sources of fiber are good for you, include them in your diet.
- give up on squats
You probably do them incorrectly exerting too much effort on your lower back or aggravating spinal Curvature. It makes your tummy more prominent. So you should replace squats with planks.
- perform different exercises
Don’t overexert any single part of your body; try circuit training, that way you’ll work every muscle group. Also, drink more water and go with easily digested foods such as green vegetables and light proteins such as fish and chicken.

Mommy’s Belly

After giving birth the building looks like you’re pregnant again. Why? Well, it’s caused by a few reasons.
- too little time for yourself
The uterus lowers itself after birth and achieving results becomes harder than it was before pregnancy. It will take at least six weeks to return to your normal size.
- you started training too early
It’s better to have a rest of two to three months after giving birth before taking up exercise. Don’t rush to the gym; now it’s better to spend time with your baby.
- weak muscles of the pelvis
Muscles of the pelvis like other muscles else need to be regularly trained. There are a lot of special exercises and simulators for this, just choose your favorites.
How to get rid of mommy’s belly? It’s easy when you put some effort into this
- consume healthy fat
Try to consume healthy fats every day; nuts, vegetable oil, and olives. It helped you fight fatigue. Which is a bonus for mom? Also, include fish oil in your diet
- do KEGEL exercises
They act as a natural corset for your body strain and relax the pelvic floor muscles 15 to 20 times and repeat this exercise 5 times a day the results will come very soon
- stuck in your belly
It’s a healthy habit that will tone your muscles without overexerting them; give it a try.
- give up on squats and crunches
These are the worse for your body after birth, let it recover first. Don’t forget to take afternoon naps and do stretching; before sleep, cover the windows and let yourself sleep during the day. The sleep hormones will intensify fat burning.

Inflated Belly

Your stomach is flat in the morning but grows during the day regardless of whether you have excess weight. It’s caused by food allergy, sluggish bowels, intestinal flora imbalance.
Here are easy ways to get rid of it
- exclude foods that don’t go well with your body
You should cut gluten bread pasta, alcohol, yeast cakes, and beer and process dairy products such as cheese milk, and butter out of your diet
- eat more fresh vegetables, meats, chicken, and fish
Try to avoid bread and pastries for two weeks and see if your belly stops swelling
- never skip breakfast
Make it the largest of your meals as digestion is at its peak in the morning. Don’t eat at night, chose your food thoroughly and drink a lot of water
- ad pre and probiotics in your diet Swelling may be a sign of imbalance intestinal flora premium probiotics are present in sour cream and fruit and vegetables including cabbage, garlic, and onion. Remember that a healthy stomach is a flat stomach
- breathing
Do the following exercise every morning; lie on your back, relax completely, inhale and exhale 10 times deeply.

Now you know that a big belly isn’t always caused by excess weight. Lots of reasons cause this problem and there are lots of solutions that can solve this.

Pleural Effusion

What is a pleural effusion?

Pleural effusion is a common clinical problem that can complicate many medical conditions. Breathlessness is the most common symptom of pleural effusion of any cause and the most common reason for pleural drainage.
It can pose a diagnostic dilemma to the treating physician because it may be related to disorders of the lung or pleura, or to a systemic disorder. Patients most commonly present with dyspnea, initially on exertion, predominantly dry cough, and pleuritic chest pain. To treat pleural effusion appropriately, it is important to determine its etiology. However, the etiology of pleural effusion remains unclear in nearly 20% of cases.
The diagnostic evaluation of pleural effusion includes chemical and microbiological studies, as well as cytological analysis, which can provide further information about the etiology of the disease process.
The physiological mechanisms underlying breathlessness in patients with a pleural effusion are unclear and likely to be multifactorial with patient-related and effusion-related factors contributing.